Endocrine System, part 1 - Glands & Hormones: Crash Course A&P #23
Does statin therapy influence steroid hormone synthesis?Menstrual cycle characteristics are markers of endocrine milieu. However, associations between age at menarche and adulthood sex steroid hormone levels have been sterkid, and data on menstrual characteristics and non-sex steroid hormones are sparse. Geometric means and tests for trend were calculated using multivariable general linear models. Menstrual cycle steroid hormone endocrine system and steroid hormone, prolactin, steroid hormone endocrine system growth factor levels in premenopausal women Hcg testosterone study cycle characteristics are markers of endocrine milieu. Electronic availability is being checked
You are logged in as InternetUser Do you really wish to logout? Do you wish to logout? Home About Partners Help Contact. Your search is being executed. Project search Search result Actual Project Login. Community programme of research on environmental hormones and endocrine disruptors. Texts for this project. German French Italian English Key words. Partners and International Organizations. Frame Research Programme - 3.
Institute of Freshwater Ecology UK. The general objectives of the programme, involving EAWAG, were to examine the occurrence and distribution of endocrine-disrupting effluents across a range of European countries, using existing fish-exposure techniques for the detection of reproductive interference. Those effluents which were shown to be capable of interfering with the fish endocrine system were then analysed for the principal causative agents.
Another objective was to collect new information on the impacts of endocrine disrupters on aquatic wildlife. Further objectives were to develop and improve in vitro tools for the rapid detection of endocrine disrupters and to investigate the application of existing in vitro techniques for the direct screening of complex effluents. Using the in vivo fish vitellogenin VTG bio-assay, four out of seventeen municipal effluents tested in eight European countries were non-estrogenic, seven were weakly and six were strongly estrogenic, while of the eight industrial effluents tested in eight countries, only two were strongly and one weakly estrogenic, none of these coming from paper mills.
Estrogenic potential expressed as estradiol equivalents, calculated based on measured steroid hormone concentrations on the other hand often matched YES activity. Population studies showed that the numbers of juvenile brown trout were significantly lower in the polluted downstream sites of the River Wyna than in the unpolluted headwaters. Exposure of brown trout eggs to river water downstream of sewage effluents resulted in a temperature-independent acceleration of embryonic development to the median eye stage but a delay in the time to hatch.
Again it is not possible to link this directly to endocrine disruption at this stage, but it is interesting to note that the Finnish partner also reported a delay in the time to hatch in zebrafish eggs exposed to a municipal wastewater treatment plant effluent. EAWAG undertook to investigate a rainbow trout gonad cell line RTG-2 for estrogen-sensitive genes and their suitability for the development of new in vitro screening tools.
The RTG-2 cell line was successfully transfected with an estrogen-responsive reporter gene construct and from this, a new in vitro estrogen screen was developed.
The assay showed a similar range of sensitivity as did the mammalian-based systems and, therefore, it is reasonable to use the more amenable mammalian receptor-based assays for environmental monitoring and screening. Alternative project number English. Partners and International Organizations English.
References in databases English.
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Hochschulschriften Innsbruck / Modeling modulators for steroid hormone actions
containing "steroid hormone level" – German-English dictionary and search the growth hormone is the most important gland in the endocrine system and. example sentences containing "Steroidhormone" – English-German dictionary and in the endocrine glands and transported to target tissue by the blood. 11 Oct Determination of steroid hormones, hormone conjugates and macrolide antibiotics in influents and effluents of sewage treatment plants utilising.