Kulim Kht Attension SIGMA FORCE TENSIOMETER CMC
Keine Suchtreffer zu: download/datasheet/167487Use of this information is subject methyl stearate sds copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice. No data on skin sensitising properties methyl stearate sds the substance itself are available. Therefore a weight of evidence approach is applied with data on structurally related substances. As the data is inconclusive and equivocal, skin sensitising properties of the target substance cannot be excluded. The contact sensitizing potential of the test item was assessed in vivo using an LLNA test.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice. No data on skin sensitising properties on the substance itself are available. Therefore a weight of evidence approach is applied with data on structurally related substances. As the data is inconclusive and equivocal, skin sensitising properties of the target substance cannot be excluded.
The contact sensitizing potential of the test item was assessed in vivo using an LLNA test. The study was performed according to OECD , adopted in A control group of 4 females was treated with the vehicle only. Five days after the first topical exposure the proliferative response of activated lymph node cells was assessed by the injection of 3H- Methylthymidine this is incorporating into the lymph node cells.
No mortality and no signs of systemic toxicity were observed. Also, no skin irritation was observed at the tested concentrations. A test item is regarded as a sensitizer if the exposure resulted in 3- fold or greater Stimulation Index S.
For the test item S. The calculated EC3 of the test item was The test item is therefore considered to be a skin sensitizer RCC In the main study, 3 groups with each 5 females were treated with A control group of 5 females was treated with the vehicle only.
Five days after the first topical exposure, the proliferative response of activated lymph node cells was assessed by the injection of 3H- Methylthymidine, which is incorporated into lymph node cells of treated animals relative to the amount which is recorded for control lymph nodes stimulation index S. No mortality and no clinical signs were observed, the body weights of all animals were within the normal range. In this study, Stimulation Indices of 1.
The EC3 value could not be calculated, since none of the tested concentrations induced an S. After a weekly epidermal induction 0. Because of the high number of positive responses in the control group, the data are judged to be inconclusive and insufficient for classification purposes Henkel For CAS a guinea pig maximisation test according to GLP principles and OECD TG was performed with Pirbright-Hartley 20 animals per dose group, 10 animals for the control group to assess the skin sensitising potential of the test substance.
Induction was performed intradermally 0. The substance is therefore not considered to be sensitizing to the skin Henkel Though the available data from structural analogues was not consistent, the substance should be classified for precautionary reasons, as Skin Sens.
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Endpoint summary Stability Endpoint summary Phototransformation in air Hydrolysis Phototransformation in water Phototransformation in soil Biodegradation Endpoint summary Biodegradation in water: Ecotoxicological Summary Aquatic toxicity Endpoint summary Short-term toxicity to fish Long-term toxicity to fish Short-term toxicity to aquatic invertebrates Long-term toxicity to aquatic invertebrates Toxicity to aquatic algae and cyanobacteria Toxicity to aquatic plants other than algae Toxicity to microorganisms Endocrine disrupter testing in aquatic vertebrates — in vivo Toxicity to other aquatic organisms Sediment toxicity Terrestrial toxicity Endpoint summary Toxicity to soil macroorganisms except arthropods Toxicity to terrestrial arthropods Toxicity to terrestrial plants Toxicity to soil microorganisms Toxicity to birds Toxicity to other above-ground organisms Biological effects monitoring Biotransformation and kinetics Additional ecotoxological information.
Administrative data Description of key information Key value for chemical safety assessment Justification for classification or non-classification. Administrative data Description of key information No data on skin sensitising properties on the substance itself are available.
/ Fatty Acid Methyl Ester Mixture # Relevante identifizierte [email protected] gaytaboo.xyz Restek GmbH . Page 6 of 6. Methyl stearate. Methyl. Methyl stearate, mixture of homologs, ACROS Organics™ kg; Plastic jerry can Methyl stearate, mixture of homologs, ACROS Sicherheitsdatenblatt (SDS). Stearinsäure-methylester. zur Synthese Methylstearat, Octadecansäure- methylester. Stearinsäure-methylester. Summenformel C19H38O2. Molare Masse (M).